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首頁/藥靶模型/免疫治療

顯示
列表

GPCR靶點(diǎn)細(xì)胞

Class A（Rhodopsin） Class B1（Secretin） Class C（Glutamate） Orphan and other 7TM Parental Cell

免疫治療

Fc Effector T Cell Activation Co-Stimulatory Co-Inhibitory Other Immune Checkpoint Combination Cytokine&Growth Factor TAA TLR STING Other

TAA（Mouse Model）

5T4 B7H3 B7H4 BCMA CD123 CD138 CD19 CD20 CD22 CD24 EpCAM CD30 CD33 CD38 CD70 CD73 CD74 CD79 CDHs CEACAMs CLDNs CLEC12A DDR1 DLLs DLK1 EpCAM ERBBs FAP FRα GPC3 GPRC5D GUCY2C IL2R KK-LC-1 LILRBs LRRC15 LY6G6D MET MSLN MUCs Nectin4 OVA PDL1 PSMA PTK7 RORs SLC39A6 SSTR2 TF TFRC TROP2

激酶靶點(diǎn)

AKT AXL BCR-ABL1 BTK BRAF c-Kit CLIP1-LTK CSF1R CSF3R EGFR EML4-ALK ERBB4 ETV6-ARG ETV6-KDR FGFRs FLT3 HER2 JAK2 KRAS MET NTRKs PDGFRA PIMs RET ROS1 Control

示蹤細(xì)胞

腸肺肝淋巴卵巢腦膀胱皮膚前列腺乳腺舌腎胃血液咽胰腺子宮

耐藥細(xì)胞

阿霉素多西他賽/紫杉醇氟維司群吉非替尼卡博替尼康士得克卓替尼賽沃替尼順鉑他莫昔芬長春新堿長期雌激素缺乏其他耐藥細(xì)胞

信號調(diào)控

信號調(diào)控細(xì)胞質(zhì)粒

其他細(xì)胞

BCL2 DMPK Ion Channel Nuclear Receptor SARS COV2 Spike Transporter Other cell models

試劑耗材

熒光素酶檢測試劑盒 cAMP 檢測試劑盒耗材

免疫治療

背景

免疫治療是指應(yīng)用免疫學(xué)的原理和方法，通過調(diào)節(jié)免疫細(xì)胞的功能來達(dá)到治療疾病的方法。目前的免疫治療主要針對兩大類疾病，一類是腫瘤相關(guān)的免疫治療，主要是通過將免疫細(xì)胞或效應(yīng)分子輸入體內(nèi)，增強(qiáng)或抑制某些免疫相關(guān)靶點(diǎn)來提高腫瘤細(xì)胞的免疫原性和對應(yīng)效應(yīng)細(xì)胞殺傷的敏感性激發(fā)和增強(qiáng)機(jī)體抗腫瘤免疫應(yīng)答，從而協(xié)同機(jī)體免疫系統(tǒng)殺傷腫瘤，抑制腫瘤生長，是一種相對安全，長效，廣譜的腫瘤治療方法;另一類則主要針對自身免疫相關(guān)疾病的治療靶點(diǎn)，通過開發(fā)抑制這些靶點(diǎn)功能的相關(guān)藥物，降低機(jī)體異常的免疫反應(yīng)水平，從而達(dá)到緩解自身免疫疾病的目的。

免疫治療

為滿足針對免疫治療靶點(diǎn)藥物的研發(fā)，科佰生物為您提供一系列相關(guān)靶點(diǎn)的細(xì)胞篩選模型，如IL12/4-1BB/ERBB3/CD28/PD1等，助力免疫治療藥物的開發(fā)。

分類	靶點(diǎn)	名稱	貨號
Fc Effector	ADCC/ADCP	ADCC Bioassay Effector Cell F variant (Low Affinity)- Fcγ-NFAT/Jurkat	CBP74002
	ADCC/ADCP	ADCC Bioassay Effector Cell V variant (High Affinity)-Fcγ-NFAT/Jurkat	CBP74003
	ADCC/ADCP	Mouse ADCC Bioassay Effector Cell	CBP74076
	ADCC/ADCP	ADCP Bioassay Effector Cell FcγRIa -NFAT/Jurkat	CBP74105
	ADCC/ADCP	ADCP Bioassay Effector Cell FcγRIIa (H variant) -NFAT/Jurkat	CBP74106
	ADCC/ADCP	ADCP Bioassay Effector Cell FcγRIIa (R variant) -NFAT/Jurkat	CBP74004
T Cell Activation	FcγR	FCGR2A/HEK293	CBP74077
	FcγR	FCGR2A（FcγRIIa）/CHO	CBP74074
	FcγR	FCGR2B/HEK293	CBP74078
	FcγR	FCGR2B（FcγRIIb）/CHO	CBP74075
	FcγR	FCGR2B/TCR Activator/CHO	CBP74096
	FcγR	hFGFR2b Effector Reporter Cell	CBP74196
	FcγR	mouse FCGR2B/CHO	CBP74100
	FcγR	mouse FCGR2B/TCR Activator/CHO	CBP74101
	FcγR	FCγR aAPC Cell	CBP74185
	N/A	TCR Activator/CHO	CBP74050
	N/A	TCR Activator/Raji	CBP74015
	N/A	NFAT-Luc/Jurkat	CBP74025
	N/A	FOXP3 promoter-Luc/Jurkat	CBP74011
	N/A	IL2 promoter-Luc/Jurkat	CBP74014
	N/A	NFκB-Luc/Jurkat	CBP74031
Immune Checkpoint	BDCA2	BDCA2 Effector Reporter Cell	CBP74226
	VSIG4	VSIG4/CHO	CBP74234
	CD200-CD200R	CD200R Effector Reporter cell	CBP74179
	CD200-CD200R	CD200 Target cell	CBP74180
	CD24	CD24/HEK293	CBP74191
Co-Stimulatory	4-1BB	41BB/NFκB-Luc/Jurkat	CBP74062
	4-1BB	41BB/NFκB-Luc/HEK293	CBP74045
	4-1BB	41BB/HEK293	CBP74040
	4-1BB	41BB/CHO	CBP74093
	BCMA	BCMA/NFκB-Luc/HEK293	CBP74072
	CD27-CD70	CD27/NFκB-Luc/Jurkat	CBP74007
	CD27-CD70	CD70/CHO	CBP74008
	CD27-CD70	CD27/HEK293	CBP74039
	CD27-CD70	CD27/CHO	CBP74033
	CD28-CD80/86	CD28 Effector Reporter Cell	CBP74099
	CD28-CD80/86	CD28 Effector Reporter-2 Cell	CBP74104
	CD28-CD80/86	CD80/CHO	CBP74069
	CD28-CD80/86	CD86/CHO	CBP74070
	CD40	CD40/NFκB-Luc/HEK293	CBP74009
	CD40	CD40/HEK293	CBP74041
	CD40	CD40/CHO	CBP74034
	DR3-TL1A	DR3 Effector Reporter Cell	CBP74236
	DR3-TL1A	TL1A Target Cell	CBP74252
	DR3-TL1A	TL1A CHO	CBP74251
	GITR-GITRL	GITR/NFκB-Luc/Jurkat	CBP74012
	GITR-GITRL	GITR/CHO	CBP74036
	GITR-GITRL	GITRL/CHO	CBP74094
	ICOS-ICOSL	ICOS Effector Reporter Cell	CBP74063
	ICOS-ICOSL	ICOSL/CHO	CBP74068
	MICA	MICA/CHO	CBP74184
	NCR1	NCR1(NKp46) Effector Reporter Cell	CBP74220
	NCR3	NCR3(NKp30) Effector Reporter Cell	CBP74239
	NKG2D	NKG2D Effector Reporter Cell	CBP74222
	OX40	OX40/NFκB-Luc/Jurkat	CBP74061
	OX40	OX40/NFκB-Luc/HEK293	CBP74017
	OX40	OX40/HEK293	CBP74049
	OX40	OX40/CHO	CBP74038
	TMIGD2-HHLA2	HHLA2(B7H7) aAPC Cell	CBP74194
	LTBR	LTBR Effector Reporter Cell	CBP74259
	TREM1	TREM1 Effector Reporter Cell	CBP74204
	TREM2	TREM2 Effector Reporter Cell	CBP74232
	TACI	hTACI Effector Reporter Cell	CBP74219
Co-Inhibitory	B7H3	4ig-B7H3(CD276)/CHO	CBP74141
	B7H3	4ig-B7H3(CD276)/THP-1	CBP75062
	BTLA-HVEM-LIGHT	BTLA Effector Reporter Cell	CBP74118
	BTLA-HVEM-LIGHT	BTLA/SHP2 Reporter Cell	CBP74177
	BTLA-HVEM-LIGHT	HVEM/U2OS Cell	CBP74178
	BTLA-HVEM-LIGHT	HVEM/TCR Activator/CHO	CBP74082
	BTLA-HVEM-LIGHT	HVEM/NFκB-Luc/Jurkat	CBP74013
	BTLA-HVEM-LIGHT	HVEM/HEK293	CBP74047
	BTLA-HVEM-LIGHT	HVEM/CHO	CBP74037
	BTLA-HVEM-LIGHT	LIGHT/CHO	CBP74029
	CD161-CLEC2D	CD161 Effector Reporter Cell	CBP74137
	CD161-CLEC2D	CLEC2D aAPC Cell	CBP74138
	CTLA4	CTLA4/ IL-2 promoter Reporter/Jurkat	CBP74084
	CTLA4	CTLA4/HEK293	CBP74046
	CTLA4	CTLA4/CHO	CBP74035
	HLA-G	B2M-associated HLA-G/aAPC Cell	CBP74189
	HLA-G	B2M-free HLA-G/aAPC Cell	CBP74190
	KIR3DL3-HHLA2	KIR3DL3 Effector Reporter Cell	CBP74193
	KIR3DL3-HHLA2	TMIGD2 Effector Reporter Cell	CBP74202
	LAG3	LAG3/NFAT-Luc/Jurkat	CBP74060
	LAG3	LAG3/IL-2-Luc/Jurkat	CBP74079
	LAG3	LAG3/HEK293	CBP74051
	LAG3	LAG3/CHO	CBP74052
	LILRB1	LILRB1 Effector Reporter Cell	CBP74187
	LILRB2	LILRB2 Effector Reporter Cell	CBP74188
	LILRB4	LILRB4 Effector Reporter Cell	CBP74102
	LILRB4	APOE/TCR Activator/CHO	CBP74107
	LILRB4	ANGPTLx/TCR Activator/CHO	CBP74103
	NKG2A-HLA-E	NKG2A Effector Reporter Cell	CBP74241
	NKG2A-HLA-E	HLA-E aAPC Cell	CBP74242
	PD1-PDL1/2	PDL1/HEK293	CBP74001
	PD1-PDL1/2	PD1/NFAT-Luc/Jurkat	CBP74018
	PD1-PDL1/2	PDL1/CHO	CBP74032
	PD1-PDL1/2	PD1/HEK293	CBP74042
	PD1-PDL1/2	PD1/CHO	CBP74043
	PD1-PDL1/2	PDL2/CHO	CBP74064
	PD1-PDL1/2	PDL2/TCR Activator/CHO	CBP74065
	PD1-PDL1/2	PDL1/TCR Activator/CHO	CBP74066
	PD1-PDL1/2	PDL1/Raji	CBP74095
	PD1-PDL1/2	PD1-IL2 Pathway Effector Reporter Cell	CBP74144
	PD1-PDL1/2	PDL1/aAPC/Raji	CBP74145
	PD1-PDL1/2	PD1/SHP2 Reporter Cell	CBP74224
	PD1-PDL1/2	PD1/SHP1 Reporter cell	CBP74231
	PD1-PDL1/2	PDL1 Target Cell(Suspension)	CBP74237
	PD1-PDL1/2	PDL1 Target Cell (Adherent)	CBP74240
	PD1-PDL1/2	PDL1 A549	CBP74245
	PVRIG-CD112	PVRIG(CD112R) Effector Reporter Cell	CBP74120
	PVRIG-CD112	CD112/TCR Activator/CHO	CBP74121
	SIRPɑ-CD47	SIRPɑ Effector Reporter Cell	CBP74122
	SIRPɑ-CD47	CD47+ Target Cell	CBP74124
	TIGIT-CD155	TIGIT/NFAT-Luc/Jurkat	CBP74020
	TIGIT-CD155	CD155/TCR Activator/CHO	CBP74073
	TIGIT-CD155	CD155/CHO	CBP74067
	TIM-3	TIM-3 Effector Reporter Cell	CBP74112
	TIM-3	TIM-3 Target cell	CBP74238
	N/A	PD1&CTLA4 Dual Effector Reporter Cell	CBP74150
	N/A	PDL1 CD80&CD86 aAPC Cell	CBP74151
	N/A	PD1&TIGIT Dual Effector Reporter Cell	CBP74126
	N/A	PDL1&CD155 TCR Activator CHO	CBP74127
	N/A	PD1&LAG3 Dual Effector Reporter Cell	CBP74147
	N/A	PDL1 MHCII APC Cell	CBP74146
	N/A	PD1&41BB Dual Effector Reporter Cell	CBP74172
	N/A	PD1&OX40 Dual Effector Reporter Cell	CBP74163
	N/A	PDL1 aAPC Cell	CBP74164
N/A	SIRPα&CD47 Dual Effector Reporter Cell	CBP74123
N/A	SIRPɑ&PD1 Dual Effector Reporter Cell	CBP74154
N/A	CD47&PDL1 Dual Target Cell	CBP74155
N/A	TIGIT&PVRIG Dual Effector Reporter Cell	CBP74167
N/A	CD155&CD112 Dual aAPC Cell	CBP74168
Cytokine&Growth Factor	Activin	Activin A Effector Reporter Cell	CBP74225
	Activin	ACVR2A CHO	CBP74248
	Activin	ACVR2B CHO	CBP74249
	BNP/NPR1	BNP/NPR1 Effector Reporter Cells	CBP74198
	CSF1R	CSF1R/SRE-Luc/HEK293	CBP74010
	CSF1R	CSF1R/HEK293	CBP74048
	EGF	SRE-Luc/HEK293	CBP74030
	EPO	hEPO Effector Reporter Cell	CBP74169
	FGF21/KLB	KLB Effector Reporter Cell	CBP74209
	GDF	hGDF/GFRAL&RET Effector Reporter Cell	CBP74186
	GHR	hGHR Effector Reporter Cell	CBP74203
	GM-CSF	hGM-CSF Effector Reporter Cell	CBP74149
	IFN	ISRE-Luc/HEK293	CBPB0005
	IFN	ISRE-Luc/THP-1	CBPB0015
	IFN	GAS-Luc/THP-1	CBPB0014
	IL1	IL1 Effector Reporter Cell	CBP74253
	IL10	IL10 Effector Reporter Cell	CBP74158
	IL11	hIL11 Effector Reporter Cell	CBP74114
	IL12	IL12 Effector Reporter Cell	CBP74134
	IL18	hIL18 Effector Reporter Cell	CBP74173
	IL2/IL15	hIL2/IL15 Dual Effector(hCD122/hCD132) Reporter Cell	CBP74170
	IL2/IL15	hIL2/IL15 Dual Effector(hCD25/hCD122/hCD132) Reporter Cell	CBP74192
	IL2/IL15	hIL2/IL15 Dual Effector (mCD25/hCD122/mCD132) Reporter Cell	CBP74109
	IL21	hIL21 Effector Reporter Cell	CBP74183
	IL22	IL22 Effector Reporter Cell	CBP74175
	IL22	hIL19 IL20 IL24 Triple Effector Reporter Cell	CBP74223
	IL22	hIL20 IL22 IL24 Triple Effector Reporter Cell	CBP74228
	IL23	IL23 Effector Reporter Cell	CBP74130
	IL27	IL27 Effector Reporter Cell	CBP74199
	IL31	IL31 Effector Reporter Cell	CBP74159
	IL31	Canine IL31 Effector Reporter Cell	CBP74235
	IL33	hIL33 Effector Reporter Cell	CBP74176
	IL36	IL36 Effector Reporter Cell	CBP74119
	IL4/IL13	hIL4/IL13 Dual Effector Reporter Cell	CBP74110
	IL5	hIL5 Effector Reporter Cell	CBP74182
	IL7	hIL7 Effector Reporter Cell	CBP74221
	IL9	hIL9 Effector Reporter Cell	CBP74207
	KDR	VEGF(KDR) Effector Reporter Cell	CBP74162
	NGF	NGF/hTRKA Effector Reporter Cell	CBP74174
	NGF	NGF/Canine TRKA Effector Reporter Cell	CBP74230
	OSMR	OSMR Effector Reporter Cell	CBP74157
	PRL	hPRL Effector Reporter Cell	CBP74227
	RANK-RANKL	RANK Effector Reporter Cell	CBP74125
	RANK-RANKL	Membrane Anchored hRANKL Cell	CBP74160
	TIE2	TIE2/HEK293	CBP74161
	TNFα	Membrane Anchored TNFα Cell (Adherent)	CBP74152
	TNFα	Membrane Anchored TNFα Cell (Suspended)	CBP74153
	TPO	TPO Effector Reporter Cell	CBP74165
	TPOR	TPOR(Ligand Dependent)/BaF3	CBP73266
	TSLP	TSLPR/IL7R/BaF3	CBP74136
	TSLP	hTSLP Effector Reporter Cell	CBP74171
	VEGF	Membrane Anchored VEGF Cell	CBP74156
	WNT	Wnt Effector Reporter Cell	CBP74166
	WNT	SOST Effector Reporter Cell	CBP74247
	WNT	DKK1 Effector Reporter Cell	CBP74200
	WNT	DDR1 CHO	CBP74256
TAA	5T4	5T4 CHO	CBP74261
	CEACAM5	CEACAM5 CHO	CBP74257
	CLDN6	hClaudin 6(CLDN6)/CHO	CBP74181
	CLDN18.2	Claudin18.2/AGS	CBP74131
	CLDN18.2	Claudin18.2/CHO	CBP74139
	CLDN18.2	Claudin18.2/ HGC27	CBP74133
	CLDN18.2	Claudin18.2/ KATOIII	CBP74132
	CLDN18.2	Claudin18.2/Miapaca2	CBP74142
	CLDN18.2	Claudin18.2/NCI-N87	CBP74148
	CLDN18.2	Claudin18.2/NUGC4	CBP74135
	CLDN18.2	Claudin18.2/PANC-1	CBP74143
	DLL3	DLL3 CHO	CBP74254
	ERBB2	ERBB2 CHO	CBP74246
	ERBB3	hERBB3(HER3)/CHO	CBP75069
	ERBB3	ERBB3(HER3)/MDA-MB-231	CBP73348
	ERBB4	ERBB4/CHO	CBP73316
	FAP	FAP CHO	CBP74255
	FGFR1	FGFR1/HEK293	CBP75067
	FGFR2	FGFR2C/HEK293	CBP75066
	GPC3	GPC3 CHO	CBP74243
	LRRC15	LRRC15 CHO	CBP74250
	MERTK	mouse MERTK/CHO	CBP73398
	Notch1	Notch1/HEK293	CBP75052
	Nectin4	hNectin4/PC-3	CBP74205
	PSMA	PSMA/22RV1	CBP74210
	PSMA	PSMA/PC-3	CBP74206
	ROR1	hROR1/CHO	CBPG0100
	TF	TF CHO	CBP75078
TLR	TLR2	TLR2/NFκB-Luc/HEK293	CBP74113
	TLR3	TLR3/NFκB-Luc/HEK293	CBP74057
	TLR4	TLR4/NFκB-Luc/HEK293	CBP74128
	TLR5	TLR5/NFκB-Luc/HEK293	CBP74053
	TLR7	TLR7/NFκB-Luc/HEK293	CBP74090
	TLR8	TLR8/NFκB-Luc/HEK293	CBP74021
	TLR9	TLR9/NFκB-Luc/HEK293	CBP74091
STING	N/A	ISRE-Luc/NFκB-SEAP/THP-1	CBP74097
	N/A	ISRE-Luc/Raw264.7	CBP74098
	N/A	IRF5-KO/NFκB-SEAP/THP-1	CBP74212
	N/A	cGAS-KO/NFκB-SEAP/THP-1	CBP74214
	N/A	TREX1-KO/NFκB-SEAP/THP-1	CBP74215
	N/A	H232-hSTING-KI/NFκB-SEAP /THP-1	CBP74216
	N/A	R232-hSTING-KI/NFκB-SEAP/THP-1	CBP74217
	N/A	S154-hSTING-KI/NFκB-SEAP/THP-1	CBP74218

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理：18240630236 全國銷售經(jīng)理：18066071954
診斷標(biāo)準(zhǔn)品聯(lián)系方式：華東銷售經(jīng)理：15000320447 華北銷售經(jīng)理：18131625521 華南銷售經(jīng)理：13484295986 華中&西南銷售經(jīng)理：13871580511 全國銷售經(jīng)理：13484295986

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