c-Kit W557G/BaF3
CBP73293
詢 價
留 言
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Introduction | |
|
Cell Line Name： |
c-Kit W557G/BaF3 |
|
Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
|
Application: |
Anti-proliferation assay and PD assay |
|
Freeze Medium: |
90% FBS+10% DMSO |
|
Complete Culture Medium: |
RPMI-1640+10%FBS |
|
Mycoplasma Status: |
Negative |
| II. Background | |
|
KIT W557G lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 16226710). W557G results in constitutive phosphorylation of Kit in cell culture (PMID: 23567324), and therefore, is predicted to lead to a gain of Kit protein function. |
|
| III. Representative Data | |
|
1. WB of c-Kit W557G/BaF3
|
|
|
2. Sanger of c-Kit W557G/BaF3
|
|
|
3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 c-KIT W557G Cells (C4). |
|
|
|
|
