JEKO-1(人套細(xì)胞淋巴瘤細(xì)胞)
CBP60275
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I. General information | |
Synonyms: | JEKO-1 |
Background: | The JeKo-1 Mantle cell lymphoma (MCL) cell line was established from peripheral blood mononuclear cells of a patient with a large cell variant of MCL showing leukemic conversion. |
Species: | Homo sapiens, human |
Tissue: | peripheral blood, Mantle Cell Lymphoma |
Disease: | Lymphoma |
Gender: | female, 78 years |
Morphology: | lymphoblast |
Growth Mode: | suspension |
DNA Profile: | Amelogenin:X CSF1PO:9,12 D13S317:8,9 D16S539:12 D5S818:10,13 D7S820:10,11 THO1:7 TPOX:8 vWA: 14 Cobioer’s Cell Line Authentication Service |
Culture Medium: |
RPMI-1640+20%FBS JEKO-1完全培養(yǎng)基,# CBP60275M |
Cryopreservation medium: | 90%FBS+10%DMSO |
Antigen Expression: | CD3-, CD5+, CD10+, CD19+ (verified at ATCC) |
Genes Expressed: | CD3-, CD5+, CD10+, CD19+ (verified at ATCC) |
Comments: | The cells overexpress cyclin D1, Bcl-2, c-Myc and Rb proteins. Bcl-1/J(H) gene rearrangement was confirmed by polymerase chain reaction. JeKo-1 cells are highly tumorigenic in SCID mice. Ref For more information, please contact Cobioer (4008-750-250). |