AN3-CA(人子宮內膜腺癌細胞)
CBP60663
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I. General information | |
Synonyms: | AN3-CA |
Species: | Homo sapiens, human |
Tissue: | uterus; endometrium |
Disease: | adenocarcinoma |
Gender: | Caucasian,female,55years |
Morphology: | epithelial |
Growth Mode: | adherent |
Doubling Time: | 32 hrs |
DNA Profile: | Amelogenin: X CSF1PO: 12,14,15 D13S317: 12,14 D16S539: 10,14 D5S818: 11,14 D7S820: 7,10,7.1 THO1: 10,9.3 TPOX: 8,10 vWA: 14,20 Cobioer’s Cell Line Authentication Service |
Culture Medium: |
MEM + 10% FBS+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) AN3-CA完全培養(yǎng)基,# CBP60663M |
Cryopreservation medium: | 90%FBS+10%DMSO |
Antigen Expression: | Culture medium, 95%; DMSO, 5% |
Tumor Formation: | Yes, in nude mice,Yes, in the cheek pouch of cortisone treated hamsters |
Comments: | The cells exhibit ion transport activities consistent with cystic fibrosis and express the product of the CF gene (cystic fibrosis transmembrane regulator, CFTR).CFPAC-1 cells show no effect of cAMP agonists, adenyl cyclase stimulators or phosphodiesterase inhibitors on Cl- flux, but do respond to Ca++ ionophores with increase Cl- efflux. The cells have the most common form of the CF mutation, deletion of three nucleotides resulting in the absence of phenylalanine at position 508.CFPAC-1 cells have epithelial morphology and polarization with apical microvilli, tight junctions and gap junctions. For more information, please contact Cobioer (4008-750-250). |