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ERBB4 WT(NRG1b Dependent)/BaF3

CBP73257

產(chǎn)品描述
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I. Introduction

Cell Line Name:

ERBB4 WT(NRG1b Dependent)/BaF3

Host Cell:

Ba/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+10ng/ml NRG1-beta1

Mycoplasma Status:

Negative

 
II. Background

Human HER4 kinase, also known as Erb-B4, Proto-Oncogene-Like Protein C-ErbB-4, and Tyrosine Kinase-Type Cell Surface Receptor HER4, GenBank Accession No. NM_005235, a.a. 708-993, with an N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=59.5 kDa.

 
III. Representative Data

1. ERBB4 WT(NRG1b Dependent)/BaF3

2. Anti-proliferation assay

Figure 2. Anti-proliferation assay of three reference compounds on the ERBB4 WT(NRG1b Dependent)/BaF3 Stable Cell line.

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