ESR1[D538G]-GAL4 Luciferase Reporter HEK293
CBPM0004
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I. Background | |
The estrogen receptor (ER/ESR1) is a member of the nuclear hormone receptor superfamily of ligand-activated transcription factors and is expressed in the majority of luminal breast cancers . Upon binding an estrogenic ligand, this transcription factor regulates the expression of genes required for cancer cell proliferation and survival. | |
II. Introduction | |
Host Cell: | HEK293 |
Expressed gene: | ESR1[D538G]-GAL4 Luciferase |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | |
Storage: | Liquid nitrogen |
III. Description of Host Cell Line | |
Organism: | Homo sapiens, Human |
Tissue: | Embryonic kidney |
Disease: | Normal |
Morphology: | Epithelial |
Growth Properties: | Adherent |
IV. Representative Data | |