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首頁 /藥靶模型 /耐藥細(xì)胞 /其他耐藥細(xì)胞 /MCF7_ESR1 p.Y537S

MCF7_ESR1 p.Y537S

CBP61283DR

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I. Introduction
Host Cell: MCF7_ESR1 p.Y537S
Culture Medium: MEM+10%FBS+ 1%Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP)
Gi50 on 22RV.1/Docetaxel: N/A
Gi50 on 22RV.1: N/A
Mycoplasma Status: Negative
Storage: Liquid nitrogen
 
II. Description of Host Cell Line
Organism: Human
Tissue: Mammary gland, breast
Disease: Breast adenocarcinoma
Morphology: Epithelial-like
Growth Properties: Adherent

 

III. Representative DATA

Figure 1. Sanger sequencing revealed ESR1 Y537S mutation, TAT-TCT.

Figure 2. Anti-proliferation assay of AZD9496 on MCF7 ESR1 Y537S.

Figure 3. Anti-proliferation assay of Faslodex on MCF7 ESR1 Y537S.

 
 
 

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