hCLDN6(Claudin6)/PANC02
CBPG0093
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I. Background | |
CLDNs 是上皮細胞緊密連接的主要成分。CLDN6 是緊密連接家族(CLDNs)的一員,是一個四次跨膜蛋白,具有較短的胞質 N 端和 C 端胞質結構域、兩個胞外結構域(較大的 ECL1 和較小的 ECL2)和一個短的胞內環(huán)。CLDN6 可參與乳腺癌、胃癌、肝細胞癌等多種惡性腫瘤的發(fā)生發(fā)展。CLDN6 具有重要的生物學功能,其異常表達與丙型肝炎感染有關。 | |
II. Introduction | |
Host Cell: | PANC02 |
Expressed gene: | hCLDN6(Claudin6) |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+2ug/ml puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
III. Description of Host Cell Line | |
Organism: | mouse |
Tissue: | Prostate |
Morphology: | Epithelial cell like |
Growth Properties: | Adherent |
IV. Representative Data | |
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