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首頁 /診斷試劑 /用藥指導(dǎo)標準品 /他莫昔芬CYP2D6多態(tài)性 /CYP2D6*10 Reference Standard

CYP2D6*10 Reference Standard

CBPA0071

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Introduction  
Format Genomic DNA
Description CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.
   
Technical Data 
Gene CYP2D6
AA Change p.P34S
DNA Change NM_000106.6_c.100C>T
Chr position (GRCh38) NC_000022.11_g.42130692G>A
Allelic Frequency 50%
Zygosity Heterozygous
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8°C
Expiry 36 months from the date of manufacture

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