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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction | |
Format | Genomic DNA |
Description | UGT1A1, UDP-glucuronosyltransferase 1-1, is an enzyme that catalyzes the glucuronidation of substances to soluble metabolites for excretion (PMID: 28520360). Genetic polymorphisms in UGT1A1 may alter the metabolism of chemotherapy drugs such as irinotecan, resulting in severe toxicity. |
Technical Data | |
Gene | UGT1A1 |
AA Change | N/A |
DNA Change | N/A |
Chr position (GRCh38) | NC_000002.12_g.233760233_233760234delTA |
Allelic Frequency | 50% |
Zygosity | Heterozygous |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 2-8°C |
Expiry | 36 months from the date of manufacture |