詢 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction | |
Format | Genomic DNA |
Description | 人類 HLA-B*5801 等位基因與別嘌呤醇引起的嚴(yán)重皮膚不良反應(yīng)(SCARs)包括過(guò)敏綜合征(HSS),Stevens-Johnson 綜合征(SJS)和中毒性表皮壞死松解癥 (TEN) 有很強(qiáng)的關(guān)聯(lián)性,而亞洲人群,尤其是中國(guó)漢族人群攜帶該基因型的頻率為 10%~20%,因此 2012 年美國(guó)風(fēng)濕管理學(xué)會(huì)更新了痛風(fēng)管理指南,其中建議使用別嘌呤醇前,對(duì)嚴(yán)重過(guò)敏反應(yīng)的高危人群(中國(guó)裔漢族,韓國(guó)裔,泰國(guó)裔),應(yīng)該進(jìn)行 HLA-B*5801 等位基因檢測(cè)。 |
Technical Data | |
Allele 1 | HLA-B*58:01 |
Allele 2 | HLA-B*15:02 |
Buffer | Tris-EDTA |
Sanger | HLA-B*15:02 58:01 Sanger Analysis exons 2+3 |
Exon2 |
GCTCCCACTCCATGAGGTATTTCTACACCGCCATGTCCCGGCCCGGCCGCGGGGAGCCCC GCTTCATCGCAGTGGGCTACGTGGACGACACCCAGTTCGTGAGGTTCGACAGCGACGCCG CGAGTCCGAGGAYGGMGCCCCGGGCGCCATGGATAGAGCAGGAGGGGCCGGAGTATTGGG ACSGGRASACACRGAWCWYSAAGRCCWMCRCRCAGACTTACCGAGAGARCCTGCGGAWCS |
Exon3 |
GGTCTCACATCATCCAGAGGATGTATGGCTGCGACSTGGGGCCSGACGGGCGCCTCCTCC GCGGGYATGACCAGTCCGCCTACGACGGCAAGGATTACATCGCCCTGAACGAGGACCTGA GCTCCTGGACCGCGGCGGACACSGCGGCTCAGATCACCCAGCGCAAGTGGGAGGCGGCCC GTGWGGCGGAGCAGCTGAGAGCCTACCTGGAGGGCCTGTGCGTGGAGTGGCTCCGCAGAT ACCTGGAGAACGGGAAGGAGACGCTGCAGCGCGCGG |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Storage | 2-8℃ |
Expiry | 36 months from the date of manufacture |