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首頁 /診斷試劑 /腫瘤標(biāo)準(zhǔn)品 /Mutation /AI-Edigene? BRAF p.V600K Reference Standard Plus

AI-Edigene? BRAF p.V600K Reference Standard Plus

CBP10413

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Introduction 
Format Genomic DNA
Description BRAF V600E/K indicates a mutation that results in the replacement of the valine (V) at amino acid 600 of the Braf protein by either a glutamate (E) or lysine (K). V600E/K mutations are hotspot mutations in Braf that result in increased Braf kinase activity (PMID: 15035987).
   
Technical Data 
DNA Change c.1798_1799GT>AA
AA Change p.V600K
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000288602
Cosmic ID COSV56057713
Chr position(GRCh37) chr7:140453136_140453137
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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